Background: Pre Menstrual Syndrome (PMS) is not real life threatening but it can seriously alter the quality of life of many women and affect their productivity and mental health. On the other hand, physical activity is one of the factors affecting the PMS, In order to study this topic we decided to investigate levels of physical activity and Pre Menstrual Syndrome among female university students.

Methods: This cross-sectional study was conducted on 240 students of Zabol University in 2013, the subjects were chosen in several stages and questionnaires of individual characteristics, premenstrual symptoms and physical activity Beck completed. After collecting the data using SPSS version 16 Descriptive statistics and Chi-square test with a significance level of p=0.05 evaluated.

Result: The results showed that 75.8% of students had premenstrual syndrome and of these, 97 students have regular physical activity (active) and 143 non-actives (inactive) respectively. Also, the two groups (active and inactive) together were significant differences the intensity of PMS symptoms (P=0.03).

 Conclusion:  Consequently, given the high prevalence of PMS in subjects and fewer symptoms of active students compared to inactive subjects, further measures to benefit the students of the benefits of exercise appear to be necessary.