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Safari Beydokhti M, Bagheri H, Ehsaei M, Nourian J. Effect of Airway Pressure Release Ventilation Mode on IntraCranial Pressure and Cranial Perfusion Pressure in patients with Traumatic Brain Injuries : A triple-blind randomized clinical trial. Sci J Hamadan Nurs Midwifery Fac. 2017; 25 (5)
URL: http://nmj.umsha.ac.ir/article-1-1709-en.html

1- MSc of Nursing Shahroud University of Medical Sciences
2- Assistant professor of Nursing Shahroud University of Medical Sciences , baghe_h1@yahoo.com
3- Professore Mashhad University of Medical Scienses
4- Assistant Professor Shahroud University of Medical Sciences
Abstract:   (335 Views)

Traumatic brain injuries cause changes in cerebral perfusion pressure and reduce intracranial pressure and mechanical ventilation is used in order to improve ventilation and brains hemodynamic status. This study aimed to evaluate the effect of APRV mode on intracranial pressure and cranial perfusion pressure of patients with traumatic brain injuries.

50 patients with traumatic brain injury admitted to ICU of selected hospitals in Mashhad, Iran, were selected and randomly assigned in intervention (n=25) and control (n=25) groups. In control group, half an hour and 1 hour after ventilation with SIMV/PSV mode, intracranial pressure and cranial perfusion pressure parameters were measured. In case group, half an hour after ventilation with SIMV/PSV mode, intracranial pressure and cranial perfusion pressure parameters were measured and patients were treated with APRV mode for one hour and again, hemodynamic parameters were measured and were compared with control group. Data were analyzed using SPSS 19.

Upon to result, average age was 47.5±16.7 year no significant difference existed between the intervention and control groups regarding mean intracranial pressure (p=0.906), However, there was a significant difference between the intervention and control groups regarding mean cranial perfusion pressure (p=0.048). The results showed that ventilation with APRV mode has no effect on ICP of TBI patients and increase cerebral perfusion pressure.

APRV mode makes no change in intracranial pressure and increases cerebral perfusion pressure, so, use of this mode of ventilation to improve measures of cranial perfusion pressure in patients with traumatic brain injuries, is recommended.

     
Type of Study: Research | Subject: Nursing
Received: 2017/04/8 | Accepted: 2017/05/7 | Published: 2017/07/17

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