Introduction: The aim of this study was to compare the effect of acupressure and valerian oil on sleep satisfaction, heart rate and Heart Rate Variability in patients with acute coronary syndrome.
Methods: This study is a clinical trial on 90 patients with acute coronary syndrome. Samples of the population selected of Sample available then randomly assigned in each group. The group of acupressure with valerian oil received massage of acupoint bilatral with two drops of Valerian oil second night in hospital. Acupressure group patient, received same acupoint massage with similar technique but without oil. Patients in the control group, received massage on unreal points with similar techniques and at the same time. Patient’s heart rate was recorded at the intervention night before, during, immediately after and 5 minutes after the intervention. The satisfaction of sleep was measured by VAS criteria 
Results: The results showed that after the intervention, sleep satisfaction in the acupressure and acupressure group with valerian oil was significantly higher than the control group; the increase was statistically significant (P<0.05). There was a significant difference between mean heart rate changes during and after and immediately after intervention with basal heart rate in the three groups (P<0.0001) 
Conclusion: This study showed that Acupressure and Valerian oil can both increase sleep satisfaction, relaxation, and therefore reduce heart rate in patients with acute coronary syndrome.