Introduction & Objective: Stress is a complex phenomenon in nursing that has a number of health outcomes. Stress also imbalances psycho-physical status and reduces personal efficiency in all aspects.This study was done for determining stress frequency in clinical nurses.

Materials & Methods: A cross-sectional study was designed to assessment of job stress at clinical nurses in hospitals of Hamedan city and they were 310 nurses. The tool of data gathering was a questionnaire that was designed according to Hinshaw & Atwood test and descriptive statistic was used for approaching to goals.

Results:The results showed that 51.3% of nurses had job stress. Results also indicated that the most of job stress was among young nurses (65.5%), low salary (69%), operation rooms (70.4%), critical units (68.7%) and night sheeft (55.6%) and finaly data showed that the highest job stress was related to over work (86.2%), job tension in emergency case (76.8%) disadvocator of patients and their relatives (65.6%), work schedule (63.4%), unequal atmosphere of work (62.1%) and care taking under adverse condition (52.6%).

Counclusion : Based on the findings , stress is one of the most common risk exposure in nursing clinical , therefore nursing education  planning  must be considered and also the collected data from this research can be used for nursing and hospital managers.