Background: This study, based on Well’s meta cognitive overview(1991), is aimed to determine the role of meta cognitive belifes in developing the symptoms of depression, anxiety and stress.

Methods: In this descriptive analytical study, 120 nurses working in Be’sat hospital in Hamadan were selected based on convenience sampling. The participants were surveyed using a short meta cognitive questionnaire (MCQ30) and a short form of depression, anxiety and stress questionnaire (DASS21).

Results: The results of study showed that there is a significant relationship between metacognitive belifes and developing the symptoms of depression, anxiety and stress (p<0.05). Results of the correlation analysis showed that there is a positive relationship between depression and uncontrollability, cognitive confidence and self-confidence (p<0.05) but there wasn’t seen any meaningful relationship between depression and positive beliefs and need to control the thoughts (p>0.05). The results also demonstrated that there are significant relationships both between stress and the whole dimensions of meta cognitive belifes (positive beliefs, uncontrollability, Cognitive confidence, the need to control the thoughts and self-consciousness) (p<0.05) and between anxiety and the mentioned dimensions of meta cognitive beliefs (p<0.05).

Conclusion: Based on the results of this study, positive and negative metacognitive beliefs play roles in developing the symptoms of depression, anxiety and stress and the total score of meta-cognitive beliefs is really crucial in predicting the development of the symptoms of depression, anxiety and stress.