Introduction: Birth of child with disability can put a lot of pressure on others, especially parents and eliminate all of the those dreams and fantasies about having a healthy child and cause problems in family relations and the development of destructive and negative emotions toward their child’s.

The aim of this study was study the relationship between stress and communication patterns of mothers of educable mentally retarded children in schools for exceptional children of Hamadan City in 2015-16 curriculum year were done.

Methods: In this descriptive- correlational study, all mothers of educable mentally retarded children in Hamadan City schools for exceptional children in the 2015-16 curriculum year that consisted of 53 females and 92 males were selected. Data collected by questionnaires: demographic questionnaire, Perceived Stress Scale (PSS-14) and Assessment Scale of mother-child relationship (MCRE) and analyzed by SPSS20.

Results: The results of multiple correlation coefficient showed that stress has negative significance relationship with admission communication patterns (P=0/001), permissive (P=0/001) and rejection (P=0/001), but stress has no significance relationship with supportive patterns of communication.

Conclusion: Based on the results obtained we can conclude having a disabled child creates to the extent stress for mothers that affected their patterns of communication by it, so it is suggested to maintain health and enhance quality of life of this mothers had implement some programs.