Introduction: The aim of this study was to determine the effectiveness of acceptance and commitment therapy on depression, self-esteem and body image concerns, after the first delivery in women in Kashan. 
Methods: This was a quasi-experimental study with a pre-test and the post-test and a control group. For this purpose from all women who gave birthfot the first timein in city of Kashan, 87 patients were screened in 2016 using convenience sampling. Of them, 30 were selected, and randomly placed in two groups: experimental and control. To do the pre-test and the post-test and collect information Edinburgh Postnatal Depression Scale, Self Esteem Inventory and body image concern inventory questionnaires were used. The treatment plan of acceptance and commitment was conducted during 1 month with 8 sessions of 90 minutes and after the implementation of the post-test data was analyzed using analysis of covariance with repeated measures.
Results: The present study shows that there is a significant difference between the subjects of the experimental and control groups in terms of one of the dependent variables (depression, self-esteem and physical deformity) (F=19.19, P<0.01). The results showed that there is a significant difference between the experimental group and the control group in terms of depression (F=95.85, P<0.0001), self-esteem (F=91.65, P<0.0001), and physical deformity (F=117.04, P<0.0001). 
Conclusion: According to the results obtained we can conclude that acceptance and commitment therapy can reduce depression and concerns about body image and increase self-esteem of women after the first delivery.