Volume 29, Issue 3 (Summer 2021)                   Avicenna J Nurs Midwifery Care 2021, 29(3): 181-189 | Back to browse issues page


XML Persian Abstract Print


Download citation:
BibTeX | RIS | EndNote | Medlars | ProCite | Reference Manager | RefWorks
Send citation to:

Bahmani S, Shaoei R. Comparison of the Effect of Misoprostol and Evening Primrose oil Capsules with Misoprostol on Delivery Method in Post-Term Pregnancy: Clinical Trial. Avicenna J Nurs Midwifery Care 2021; 29 (3) :181-189
URL: http://nmj.umsha.ac.ir/article-1-2208-en.html
1- Instructor, School of Nursing and Midwifery, Kurdistan University of Medical Sciences, Sanandaj, Iran , soma.bahmani25@gmail.com
2- Associate Professor, Clinical Care Research Center, Kurdistan University of Medical Sciences, Sanandaj, Iran
Abstract:   (7669 Views)

Background and Objective: Post-term pregnancies are pregnancies that last more than 42 full weeks (294 days) from the first day of the last menstrual period. With increasing gestational age, the rate of maternal and fetal morbidity and mortality significantly increases. Among medical methods, misoprostol is widely used to prepare the cervix in post-term pregnancies. But today, due to the high side effects of misoprostol, especially the increasing need for cesarean section, some complementary medicine methods are used to prepare the cervix. The aim of this study was to compare the effect of Misoprostol and Evening primrose oil capsule with Misoprostol on delivery method in post-term pregnancies.
Material and Methods: This study was performed as a single-blind randomized clinical trial on 130 pregnant women with post-term pregnancy referring to the delivery ward of Besat Hospital in Sanandaj, Iran. The samples were selected by available sampling method and assigned to the intervention and control groups by random sampling method. In the intervention group, a 500 mg capsule of evening primrose oil was given vaginally and 25 micrograms of misoprostol were given sublingually, and in the control group, an ineffective capsule was given vaginally with 25 micrograms of misoprostol sublingually. Demographic data, clinical characteristics and delivery method were used for data collection. Data were analyzed by SPSS software version 21 and statistical tests such as Chi-square, t-test and ANOVA. P-value less than 0.05 was considered significant.
Results: Findings showed that there was no significant difference between the two groups in terms of demographic and midwifery characteristics and the two groups were homogeneous in this respect (P>0.05). But in the evening primrose oil and misoprostol group, the mean bishop score was significantly increased compared to the misoprostol group (P<0.05). Also, in the evening primrose oil and misoprostol group (12.3%), the need for cesarean section was lower than placebo and misoprostol group (41.5%) (P<0.0001).
Conclusion: The results of the study showed that the use of vaginal capsules of evening primrose oil with misoprostol compared to misoprostol alone while helping to ripening the cervix is associated with a lower rate of cesarean section.

Persian Full-Text [PDF 629 kb]   (1140 Downloads) |   |   Extended Abstract (HTML)  (1410 Views)  

✅ The results of the study showed that the use of vaginal capsules of evening primrose oil with misoprostol compared to misoprostol alone while helping to ripening the cervix is associated with a lower rate of cesarean section.


Type of Study: Original Research | Subject: Midwifery
Received: 2020/06/25 | Accepted: 2021/01/4 | Published: 2021/09/21

References
1. Cunningham, Leveno, Bloom, Spong, Dashe, Hoffman, Casey, Sheffield. Williams Obstetrics.24th.Tehran: Arjmand Pub: 2018.
2. Shahali S, Khatami F, Abbaspoor Z, Gheraghian B. The effect of vaginal evening primrose capsule on cervical ripening in nulliparous women with post-term pregnancy: A clinical trial. IJOGI. 2018;21(8):30-8.
3. Ministry of health and medical education. national guide to midwifery and childbirth services. Tehran, 2017.Retreived from https://behdasht.gov.ir.
4. Rezaie M, Seyedoshohadaei F, Nayebi M. Comparison of oral and vaginal prescription of misoprostol in labor induction of post-term pregnancies. Horizon Med Sci. 2016;22(2):103-9. [DOI:10.18869/acadpub.hms.22.2.103]
5. Eslamian L, Shahsavari H. Management and outcome of prolonged pregnancies in Shariati university hospital. Tehran Univ Med J. 2008; 65(12):48-54.
6. Hajivandi L, Montazeri S, Irvani M, Oliyai A, Haghighi zade M. Investigating the Effect of Intramuscular Dexamethas on Duration of Labor in Post Date Pregnancy. JSSU. 2013; 21 (5):555-63.
7. Teymori B, GHasemi M, Sakhavar N, Khajenouri S. Comparison of Vaginal Trinitroglycerin (TNG) and Vaginal Misoprostol in Cervical Ripening at term pregnancy. Iran. J. Obstet. Gynecol. Infertil. 2018; 20(11): 8-14. [Persian]
8. PonMalar J, Benjamin SJ, Abraham A, Rathore S, Jeyaseelan V, Mathews JE. Randomized double-blind placebo controlled study of preinduction cervical priming with 25 µg of misoprostol in the outpatient setting to prevent formal induction of labour. Arch Gynecol Obstet. 2017;295(1):33-8. [DOI:10.1007/s00404-016-4173-z] [PMID]
9. Husain S, Husain S, Izhar R. Oral misoprostol alone versus oral misoprostol and Foley's catheter for induction of labor: A randomized controlled trial. J Obstet Gynaecol Res. 2017;43(8):1270-7. [DOI:10.1111/jog.13354] [PMID]
10. Keshavarzi F, Nankoli A, Rezaie M, Fakheri T, Jalilian N, Mohammadi N, Lashni N, Khashay A. Compare amniotic infusion of normal saline and hydrocortisone with suppositories prostaglandin E2 for termination of pregnancy. J Birjand Univ Med Sci. 2012;19(2):132-139.
11. Jalilian N, Tamizi N, Rezaei M. The effect of vaginal Misoprostol and intravenous Oxytocin for labor induction, J Kermanshah Univ Med Sci. 2010 ; 14(3):e79473.
12. Sharifzadeh, F., Abbasi Dezfouli, G., Moeini Chaghervand, M., Azad, Z. Comparison of the efficacy of Glyceryl trinitrate and Misoprostol on cervical ripening for curretage in pregnant women at first trimester. Iran J Obstet Gynecol Infertil, 2015; 18(174): 6-11. [DOI:10.22038/ijogi.2015.6371]
13. Inal HA, Inal ZH, Tonguc E, Var T. Comparison of vaginal misoprostol and dinoprostone for cervical ripening before diagnostic hysteroscopy in nulliparous women. Int J Fertil Steril. 2015;103(5):1326-31. [DOI:10.1016/j.fertnstert.2015.01.037] [PMID]
14. Alinejati S, Mallah F. Comparing the Efficacy and Side Effects of Trans-Cervical Catheter and Vaginal Misoprostol on Cervical Ripening. Alborz Univ Med J. 2016;5(3):149-56. [Persian] [DOI:10.18869/acadpub.aums.5.3.149]
15. Alamiherandi R, Karamali M, Moieni A. Comparison of efficacy and side effects of oral misoprostol with oxytocin to induce labor in term pregnancy. J North Khorasan Univ Med Sci. 2012; 4(3): 303-09. [Persian] [DOI:10.29252/jnkums.4.3.303]
16. Jahdi F, Kalati M, Kashanian M, Naseri M, Haghani H. Effect of oral evening primrose capsules on ripening of the cervix in nulliparous iranian pregnant women (a randomized trial). Acta Med Mediterranea. 2016;32(Specia):1273-9. [Persian]
17. Tahermanesh K, Vahdat M, Mehdizade Kashi A, Ashouri M, Solaymani Dodaran M, Kashanian M, Alizade P et at. Evening Primrose Oil Effect on the Ease of Cervical Ripening and Dilatation before Operative Hysteroscopy. Thrita J. 2015; 4(3): e29876. [Persian] [DOI:10.5812/thrita.29876]
18. Fallah LT, Najafi A, Fathizadeh N, Khaledian Z. The effect of evening primrose oil on premenstrual syn. Sci J Hamadan Nurs & Mid. 2008;10;16(1):35-45. [Persian]
19. González CA, Guerra AS, Llano RA. Behavior of cervix during pregnancy, labor and puerperium. Ginecol Obstet Mex. 2010;78(02):132-7.
20. Beigi A, Kazemipour SM, Tabarestani H. Induction of labor in term pregnancy: Sublingual versus vaginal misoprostol. Mag Tehran Uni Med Sci. 2010; 68(3): 175-81. [Persian]
21. Dove D, Johnson P. Oral evening primrose oil: Its effect on length of pregnancy and selected intrapartum outcomes in low-risk nulliparous women. J Nurs-Midwifery. 1999; 44(3): 320-4. [DOI:10.1016/S0091-2182(99)00055-5]
22. Bayles B, Usatine R. Evening primrose oil. Am Fam Physician. 2009;80(12):1405-8.
23. Nonette DN. The effectiveness of evening primrose oil gel capsule as a cervical ripening agent during labor induction as measured by bishop score on term singleton pregnant patients. Philippine J Obstet Gynecol. 2017; 41(2):1-4.
24. Abedi Asl ZH, Pordelshahri M, Amirian M, Zare SH. Compare the effects of vaginal misoprostol and Foley catheter intracervically on cervical ripening before induction of labor at term pregnancy. Med J. 2005; 63(9): 757-63.
25. Chung JH, Huang WH, Rumney PJ, Garite TJ, Nageotte MP. A prospective randomized controlled trial that compared misoprostol, Foley catheter, and combination misoprostol-Foley catheter for labor induction. Am.J Obstet Gynecol. 2003; 189: 1031-5. [DOI:10.1067/S0002-9378(03)00842-1]

Add your comments about this article : Your username or Email:
CAPTCHA

Send email to the article author


Rights and permissions
Creative Commons License This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.

© 2024 CC BY-NC 4.0 | Avicenna Journal of Nursing and Midwifery Care

Designed & Developed by : Yektaweb