Introduction: Sexual dysfunction is one of the impacts of cancer. Several factors have affect on improving or exacerbating sexual function. This study aimed to assess predictive factors of sexual function in women with gynecologic cancer.
Methods: In this descriptive cross-sectional study (during January to June, 2016), 800 patients with gynecologic cancers from two hospitals affiliated to Qazvin University of Medical Sciences were chosen by convenience sampling method. Data was collected using demographic questionnaire and Rosen sexual function index. In order for data analysis, descriptive (e.g the mean and standard deviation for continuous data, and the number (percentage) for qualitative) nominal variables and inferential statistics like multiple linear regression analysis were done. Statistical analysis was performed using SPSS22.
Results: The mean score of sexual function among gynecologic cancer patients was reported 18.88 ±.36 (CI₉₅: 18.17-19.59) and showed low level of sexual function. The results of the linear regression model showed that duration of disease (β = -.107, P =.001), stage of the cancer (β = -.908, P =.004), type of treatment (β =.563, P =.005), and social protection (β=.341, P=.001) can significantly predict women`s sexual function. 
Conclusion: Considering the results of present study, four factors including duration of disease, stage of cancer, type of treatment and social support were found important to predict the sexual function in women with gynecological cancer. So, it is suggested to perform educational programs through media and health care centers in order to promote the awareness of patients, families, illness perception, and as the whole population.